Herb
Research Foundation News Archive |
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Zinc and genistein
together may help prevent age-related bone loss
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Several factors
lead to the decrease of bone with aging; some of this decrease may be
prevented by pharmacological and dietary intervention. A recent study
demonstrated a direct stimulatory effect of genistein on bone formation
in an in vitro tissue system. Genistein is a naturally occurring
isoflavonoid phytoestrogen found in Fabaceae plants, such as soy and red
clover. Zinc, an essential trace element, has also been shown to enhance
bone formation and inhibit bone resorption, both in vitro and in
vivo. The present study investigated the relationship between genistein
and zinc and the effects of this combination on bone metabolism of elderly
female rats. These researchers found that the isoflavonoid effect was
enhanced by zinc; the combination may have a potent role in bone loss
prevention. |
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Gao Y and Yamaguchi
M., "Zinc enhancement of genistein’s anabolic effect on bone components
in elderly female rats." Gen. Pharmac. 1998; 31(2):199-202.
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