| Andrographis herb combination effective against 
                cold and flu Two consecutive randomized, double-blind clinical trials concluded 
                that a fixed combination of Andrographis paniculata and 
                Siberian ginseng (eleuthero, Eleutherococcus senticosus) 
                was significantly more effective than placebo in relieving symptoms 
                of cold or flu. In the first trial (a pilot study of 46 subjects) 
                the total symptom score showed a tendency toward improvement, 
                while in the second (a larger, phase III clinical study involving 
                179 participants), highly significant improvement was seen in 
                both total symptom and total diagnosis scores in people taking 
                the herbal formula. For the pilot trial, subjects were treated 
                for a minimum of three and a maximum of eight days; in the phase 
                III trial, subjects took the herbal formula for exactly three 
                days. Results were assessed by both participants and physicians. 
                In both studies, throat symptoms demonstrated the most significant 
                improvement. Melchior J, Spasov AA, Ostrovkij OV, et al. Double-blind, 
                placebo-controlled pilot and phase III study of activity of standardized 
                Andrographis paniculata Herba Nees extract fixed combination 
                (Kan jang) in the treatment of uncomplicated upper-respiratory 
                tract infection. Phytomedicine 2000; 7(5): 341-350.
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